2-(Bromomethyl)-1,1-difluorocyclopropane
97%
science Other reagents with same CAS 77613-65-1
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description Product Description
Used primarily as a key intermediate in the synthesis of fluorinated pharmaceuticals and agrochemicals. Its unique strained cyclopropane ring combined with bromine and difluoromethylene groups allows for selective functionalization, making it valuable in medicinal chemistry for building bioactive molecules. Commonly employed in alkylation reactions where the bromomethyl group acts as an electrophilic site for nucleophilic substitution. Also utilized in the preparation of fluorinated analogs of natural products to enhance metabolic stability and lipophilicity. Its reactivity profile supports use in cross-coupling reactions and ring-opening transformations for developing complex fluorinated structures.
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