Used as a key intermediate in medicinal chemistry for the synthesis of bioisosteres, particularly in the preparation of bicyclo[1.1.1]pentane (BCP) derivatives that serve as replacements for phenyl or alkyne groups in drug molecules. The bromomethyl group enables further functionalization through nucleophilic substitution, allowing attachment of various pharmacophores. The tert-butyl carboxylate group serves as a protecting group for the carboxylic acid, which can be deprotected to reveal the free acid for further modification downstream. This compound is valuable in drug design for improving metabolic stability, solubility, and reducing off-target effects in small molecule therapeutics. It is commonly used in the development of CNS drugs, radiolabeled compounds, and targeted protein degraders due to the rigid, three-dimensional structure of the BCP core.