1-(Bromomethyl)adamantane
98%
Reagent
Code: #149461
CAS Number
14651-42-4
blur_circular Chemical Specifications
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Molecular Information
Weight
229.16 g/mol
Formula
C₁₁H₁₇Br
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Registry Numbers
MDL Number
MFCD00185303
thermostat
Physical Properties
Melting Point
40-45 °C
Boiling Point
226.5 °C at 760 mmHg
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Storage & Handling
Density
1.36 g/cm3
Storage
Room temperature
description Product Description
Used primarily as a versatile intermediate in organic synthesis, especially in pharmaceutical and materials chemistry. Its reactive bromomethyl group readily undergoes nucleophilic substitution, enabling the attachment of adamantane moieties to various molecules. This property is exploited in drug design to enhance metabolic stability, lipophilicity, and bioavailability. Commonly used in the preparation of adamantane-based derivatives such as antiviral agents, NMDA receptor antagonists, and ligands for catalysis. Also employed in polymer chemistry to introduce rigid, hydrophobic adamantyl units into macromolecules, improving thermal and mechanical properties. Its stability and unique three-dimensional structure make it valuable in the development of supramolecular systems and host–guest chemistry.
format_list_bulleted Product Specification
| Test Parameter | Specification |
|---|---|
| Appearance | White to Off-White to Yellow Solid or Semi-Solid or Liquid |
| Purity (%) | 97.5-100% |
| Infrared Spectrum | Conforms to Structure |
| NMR | Conforms to Structure |
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