Phosphorus tribromide is widely used as a reagent in organic synthesis, particularly for converting alcohols to alkyl bromides. This transformation is crucial in the preparation of various organic compounds, including pharmaceuticals and agrochemicals. It is also employed in the synthesis of bromoalkanes, which serve as intermediates in the production of other chemicals. Additionally, it plays a role in the preparation of organophosphorus compounds, which are used in flame retardants and plasticizers. Its strong brominating properties make it valuable in laboratory settings for introducing bromine atoms into organic molecules, facilitating further chemical modifications.