1,2,3-Tribromobenzene is primarily employed as an intermediate in organic synthesis for the production of more complex brominated aromatic compounds, particularly in pharmaceutical, agrochemical, and fine chemical industries. It is also widely used in research and development to investigate the properties, reactivity, and applications of polybrominated benzenes. Additionally, it can serve as a flame retardant in plastics, textiles, and electronic components to reduce flammability, though this application is somewhat limited due to regulatory concerns over environmental persistence and toxicity of brominated compounds.