Used as an intermediate in the synthesis of biologically active compounds, particularly in pharmaceuticals targeting central nervous system disorders. Its rigid bicyclic structure and fluorine substitutions enhance metabolic stability and blood-brain barrier penetration, making it valuable in drug design for neuroactive agents. Commonly employed in the development of enzyme inhibitors and receptor modulators where steric and electronic effects are critical. The tert-butyl carboxylate group allows for easy functionalization, enabling further chemical modifications in multi-step synthetic routes.