tert-butyl (1R,2R,5R)-2-amino-8-azabicyclo[3.2.1]octane-8-carboxylate
97%
Reagent
Code: #228705
CAS Number
1932128-35-2
blur_circular Chemical Specifications
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Molecular Information
Weight
226.32 g/mol
Formula
C₁₂H₂₂N₂O₂
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Registry Numbers
MDL Number
MFCD29048659
thermostat
Physical Properties
Boiling Point
313.2±25.0 °C(Predicted)
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Storage & Handling
Density
1.084±0.06 g/cm3(Predicted)
Storage
Room temperature
description Product Description
Used as a chiral building block in the synthesis of pharmaceuticals, particularly in the development of active pharmaceutical ingredients (APIs) requiring high enantiomeric purity. Its rigid bicyclic structure and defined stereochemistry make it valuable in designing drugs targeting central nervous system disorders, including antidepressants and antipsychotics. The tert-butyl carbamate (Boc) group facilitates protection of the amine during multi-step syntheses, allowing selective reactions at other functional sites. Commonly employed in medicinal chemistry for structure-activity relationship (SAR) studies due to its ability to influence bioavailability and receptor selectivity.
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