Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of neuroactive compounds and central nervous system agents. Its rigid bicyclic structure makes it valuable for designing potent and selective receptor modulators. Commonly employed in medicinal chemistry for constructing constrained analogs of bioactive molecules, enhancing metabolic stability and target specificity. Frequently utilized in the preparation of protease inhibitors and kinase inhibitors due to its favorable stereochemistry and functional group compatibility. Also applied in solid-phase and solution-phase peptide-like synthesis where structural rigidity is required.