Used in pharmaceutical research as a key intermediate in the synthesis of biologically active compounds, particularly in the development of central nervous system agents. Its rigid bicyclic structure and fluorine substitution enhance metabolic stability and blood-brain barrier penetration, making it valuable in designing neuroactive drugs. Commonly employed in the preparation of receptor ligands, including those targeting serotonin and dopamine receptors. Also utilized in medicinal chemistry for structure-activity relationship studies due to its stereochemical defined framework and polarity modulation from fluorine atoms.