(5-((4-(tert-Butoxycarbonyl)piperazin-1-yl) sulfonyl)-2-methylphenyl)boronic acid

98%

Reagent Code: #89331
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CAS Number 1704122-11-1

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 384.26 g/mol
Formula C₁₆H₂₅BN₂O₆S
inventory_2 Storage & Handling
Storage room temperature, dry

description Product Description

This compound, (5-((4-(tert-Butoxycarbonyl)piperazin-1-yl)sulfonyl)-2-methylphenyl)boronic acid, is primarily utilized in organic synthesis and pharmaceutical research, particularly in the development of drugs targeting various diseases. Its structure features a boronic acid group on a 2-methylphenyl ring, linked via a sulfonyl group to a piperazine moiety bearing a tert-butoxycarbonyl (Boc) protecting group. This configuration makes it valuable in Suzuki-Miyaura cross-coupling reactions, a widely used method for forming carbon-carbon bonds between the boronic acid and aryl or vinyl halides. This enables the creation of complex molecules, including potential drug candidates. Additionally, the piperazine moiety enhances its applicability in designing compounds with improved pharmacokinetic properties, such as increased solubility or bioavailability, while the Boc group protects the amine during synthesis. It is often employed in the synthesis of protease inhibitors, receptor antagonists, and other biologically active molecules.

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Size Availability Unit Price Quantity
inventory 500mg
10-20 days ฿29,860.00

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