(4-(tert-Butyl)-2-fluorophenyl)boronic acid is primarily used in organic synthesis, particularly in Suzuki-Miyaura cross-coupling reactions. This reaction is widely employed in the pharmaceutical industry to create complex organic molecules, including active pharmaceutical ingredients (APIs). The compound acts as a key intermediate in the formation of carbon-carbon bonds, enabling the construction of biaryl structures, which are common in many drugs and agrochemicals. Its tert-butyl and fluorine substituents enhance its stability and reactivity, making it a valuable reagent in the synthesis of aromatic compounds. Additionally, it is utilized in materials science for the development of organic electronic materials, such as OLEDs and photovoltaic cells, due to its ability to modify and functionalize aromatic systems.