2-tert-Butyl-pyridine-5-boronic acid is primarily used in organic synthesis, particularly in cross-coupling reactions like the Suzuki-Miyaura reaction. This reaction is widely employed in the pharmaceutical industry to create complex molecules by forming carbon-carbon bonds. The compound serves as a key intermediate in the synthesis of various active pharmaceutical ingredients (APIs) and fine chemicals. Its boronic acid group makes it highly reactive and selective in coupling with aryl or vinyl halides, enabling the production of biaryl compounds. Additionally, it is utilized in the development of materials science, including the creation of organic electronic materials and polymers. Its stability and reactivity make it a valuable tool in research and industrial applications for constructing diverse molecular architectures.