4-(N,O-Dimethylhydroxylaminocarbonyl)phenylboronic acid
98%
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This compound is a specialized phenylboronic acid derivative with a para-substituted N,O-dimethylhydroxylaminocarbonyl (Weinreb amide) group. It serves as a versatile building block in organic synthesis, particularly in palladium-catalyzed cross-coupling reactions like Suzuki-Miyaura couplings. The boronic acid moiety enables efficient formation of carbon-carbon bonds with aryl or vinyl halides, incorporating the para-Weinreb amide phenyl unit into complex molecules. The Weinreb amide functionality is particularly valuable for selective transformations into ketones or aldehydes via reaction with organometallics, enhancing its utility in multi-step syntheses. It is widely used in pharmaceutical development, agrochemical production, and materials science for creating biaryl compounds and fine-tuning molecular properties. Its balanced stability and reactivity make it a preferred reagent for advanced organic transformations.
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