(3-Fluoro-5-(piperidine-1-carbonyl)phenyl)boronic acid
98%
Reagent
Code: #188753
CAS Number
874219-43-9
blur_circular Chemical Specifications
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Molecular Information
Weight
251.06 g/mol
Formula
C₁₂H₁₅BFNO₃
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Registry Numbers
MDL Number
MFCD08235060
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Physical Properties
Melting Point
133-135 °C
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Storage & Handling
Storage
Room temperature, seal, dry
description Product Description
Used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of kinase inhibitors for cancer treatment. Its boronic acid group enables Suzuki-Miyaura cross-coupling reactions, allowing efficient construction of biaryl structures in drug molecules. The presence of fluorine enhances metabolic stability and membrane permeability in final active pharmaceutical ingredients. Commonly employed in medicinal chemistry for optimizing lead compounds due to its balanced polarity and reactivity.
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