(4-((tert-Butyldimethylsilyl)oxy)-2,6-difluorophenyl)boronic acid

98%

Reagent Code: #131606
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CAS Number 2096341-77-2

science Other reagents with same CAS 2096341-77-2

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 288.17 g/mol
Formula C₁₂H₁₉BF₂O₃Si
badge Registry Numbers
MDL Number MFCD19237185
thermostat Physical Properties
Boiling Point 317.7±52.0 °C(Predicted)
inventory_2 Storage & Handling
Density 1.12±0.1 g/cm3(Predicted)
Storage -20°C, Sealed, Inert Gas

description Product Description

Used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of kinase inhibitors and other biologically active molecules. Its boronic acid functionality enables Suzuki-Miyaura cross-coupling reactions, allowing for efficient carbon-carbon bond formation in complex molecule assembly. The silyl-protected phenol group provides a handle for further functionalization or deprotection under mild conditions, making it valuable in multi-step organic syntheses. Commonly employed in medicinal chemistry for constructing fluorinated aromatic systems with improved metabolic stability and binding affinity.

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Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿2,310.00
inventory 250mg
10-20 days ฿3,850.00
inventory 1g
10-20 days ฿10,680.00

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(4-((tert-Butyldimethylsilyl)oxy)-2,6-difluorophenyl)boronic acid
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Used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of kinase inhibitors and other biologically active molecules. Its boronic acid functionality enables Suzuki-Miyaura cross-coupling reactions, allowing for efficient carbon-carbon bond formation in complex molecule assembly. The silyl-protected phenol group provides a handle for further functionalization or deprotection under mild conditions, making it valuable in multi-step organic syntheses. Commonly

Used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of kinase inhibitors and other biologically active molecules. Its boronic acid functionality enables Suzuki-Miyaura cross-coupling reactions, allowing for efficient carbon-carbon bond formation in complex molecule assembly. The silyl-protected phenol group provides a handle for further functionalization or deprotection under mild conditions, making it valuable in multi-step organic syntheses. Commonly employed in medicinal chemistry for constructing fluorinated aromatic systems with improved metabolic stability and binding affinity.

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