(2-(2,2,2-Trifluoroethoxy)pyrimidin-5-yl)boronic acid
98%
science Other reagents with same CAS 1401163-85-6
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Used as a key intermediate in Suzuki-Miyaura cross-coupling reactions for the synthesis of biologically active compounds, particularly in pharmaceutical and agrochemical research. Its boronic acid functionality enables efficient carbon-carbon bond formation with aryl or heteroaryl halides, making it valuable in constructing complex molecules. The presence of a trifluoroethoxy group enhances metabolic stability and lipophilicity, which is beneficial in drug design, especially for targeting enzymes or receptors in medicinal chemistry programs. Commonly employed in the development of kinase inhibitors and other therapeutic agents where fluorinated heterocycles improve pharmacokinetic properties.
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