1H-Indene-2-boronic acid is widely used in organic synthesis, particularly in Suzuki-Miyaura cross-coupling reactions. This reaction is essential for forming carbon-carbon bonds, enabling the creation of complex organic molecules, including pharmaceuticals, agrochemicals, and advanced materials. Its boronic acid group acts as a key intermediate, facilitating the coupling with aryl or vinyl halides in the presence of a palladium catalyst. Additionally, it is employed in the development of sensors and molecular recognition systems due to its ability to interact with diols and other functional groups. Its versatility makes it valuable in research and industrial applications for constructing diverse chemical structures.