4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(trifluoromethyl)phenol
98%
Reagent
Code: #46245
CAS Number
1243143-45-4
blur_circular Chemical Specifications
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Molecular Information
Weight
288.0706 g/mol
Formula
C₁₃H₁₆BF₃O₃
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Registry Numbers
MDL Number
MFCD16994250
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Storage & Handling
Storage
room temperature
description Product Description
This chemical is primarily utilized in organic synthesis, particularly in cross-coupling reactions such as the Suzuki-Miyaura reaction, where it acts as a key boronic ester intermediate. Its structure, featuring a trifluoromethyl group, enhances its reactivity and selectivity in forming carbon-carbon bonds, making it valuable in the production of pharmaceuticals and agrochemicals. Additionally, the trifluoromethyl group imparts unique properties to the final compounds, such as increased metabolic stability and lipophilicity, which are advantageous in drug development. It is also employed in materials science for the synthesis of advanced organic materials, including polymers and liquid crystals, due to its ability to introduce specific functional groups into complex molecules.
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