2-(4-Methylpiperazin-1-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine
97%
Reagent
Code: #41707
CAS Number
942922-07-8
blur_circular Chemical Specifications
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Molecular Information
Weight
304.2000 g/mol
Formula
C₁₅H₂₅BN₄O₂
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Registry Numbers
MDL Number
MFCD08669592
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Storage & Handling
Storage
2-8°C
description Product Description
This compound is primarily utilized in the field of medicinal chemistry and drug development, particularly in the synthesis of biologically active molecules. Its structure, featuring a pyrimidine core with a piperazine and boronic ester group, makes it a valuable intermediate in the design of kinase inhibitors. Kinase inhibitors are crucial in targeting specific enzymes involved in various diseases, including cancer and inflammatory disorders. The boronic ester moiety is especially significant in Suzuki-Miyaura cross-coupling reactions, a widely used method in organic synthesis to create complex molecules. This enables the efficient construction of diverse chemical libraries for high-throughput screening in drug discovery. Additionally, the piperazine group enhances the compound's solubility and bioavailability, making it a useful building block in the development of pharmaceutical agents.
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