5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(trifluoromethyl)thiazole
98%
Reagent
Code: #244504
CAS Number
1415241-98-3
blur_circular Chemical Specifications
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Molecular Information
Weight
279.09 g/mol
Formula
C₁₀H₁₃BF₃NO₂S
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Registry Numbers
MDL Number
MFCD26518431
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Storage & Handling
Storage
-20°C
description Product Description
Used primarily in cross-coupling reactions, this compound serves as a key building block in the synthesis of pharmaceuticals and agrochemicals. Its boronate ester group enables Suzuki-Miyaura coupling, allowing efficient formation of carbon-carbon bonds with aryl or heteroaryl halides. The presence of the trifluoromethylthiazole moiety adds metabolic stability and lipophilicity, making it valuable in drug discovery for targeting kinases and other biological pathways. It is also employed in the development of functional materials, including organic semiconductors and fluorescent probes, due to the electron-withdrawing nature of the trifluoromethyl group and the stability of the thiazole ring.
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