tert-butyl4-(5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)piperidine-1-carboxylate
98%
Reagent
Code: #244377
CAS Number
2223046-23-7
blur_circular Chemical Specifications
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Molecular Information
Weight
388.31 g/mol
Formula
C₂₁H₃₃BN₂O₄
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Storage & Handling
Storage
Room temperature, seal, dry
description Product Description
Used in pharmaceutical synthesis as a key intermediate in Suzuki-Miyaura cross-coupling reactions to construct biaryl or heteroaryl scaffolds. Its pyridine and boronate ester groups enable selective coupling with aryl halides, making it valuable in the development of active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system drug discovery. The Boc-protected piperidine moiety allows for further functionalization and controlled deprotection during multi-step syntheses. Commonly employed in medicinal chemistry for building complex, nitrogen-containing heterocycles with improved metabolic stability and binding affinity.
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