4,4,5,5-Tetramethyl-2-(4-(2,2,2-trifluoroethoxy)phenyl)-1,3,2-dioxaborolane
98%
Reagent
Code: #244185
CAS Number
886528-42-3
blur_circular Chemical Specifications
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Molecular Information
Weight
302.1 g/mol
Formula
C₁₄H₁₈BF₃O₃
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Registry Numbers
MDL Number
MFCD22418017
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Storage & Handling
Storage
2-8°C, sealed, dry, inert gas
description Product Description
Used as a key reagent in Suzuki-Miyaura cross-coupling reactions, enabling the formation of carbon-carbon bonds in pharmaceutical and agrochemical synthesis. Its boron-containing structure facilitates coupling with aryl halides under palladium catalysis, making it valuable for constructing biaryl systems found in active pharmaceutical ingredients. The electron-withdrawing trifluoroethoxy group enhances reactivity and stability, improving coupling efficiency in complex molecule assembly. Commonly employed in late-stage functionalization due to its tolerance of various functional groups and reliable performance in both research and industrial settings.
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