4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3-(trifluoromethyl)aniline
97%
Reagent
Code: #243219
CAS Number
1259285-61-4
blur_circular Chemical Specifications
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Molecular Information
Weight
287.09 g/mol
Formula
C₁₃H₁₇BF₃NO₂
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Registry Numbers
MDL Number
MFCD16996236
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Physical Properties
Boiling Point
353.7±42.0 °C(Predicted)
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Storage & Handling
Density
1.19±0.1 g/cm3(Predicted)
Storage
2-8°C, avoiding light
description Product Description
Widely used in cross-coupling reactions, particularly in Suzuki-Miyaura coupling, this compound serves as a key building block in the synthesis of pharmaceuticals and agrochemicals. Its boronate ester group enables efficient carbon-carbon bond formation under mild conditions, making it valuable in medicinal chemistry for constructing biaryl systems. The presence of a trifluoromethyl group enhances the lipophilicity and metabolic stability of target molecules, which is advantageous in drug design. It is commonly employed in the development of bioactive compounds, including kinase inhibitors and anti-inflammatory agents. Additionally, it finds use in materials science for creating functional organic materials with tailored electronic properties.
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