4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrolo[2,3-b]pyridine
98%
Reagent
Code: #243087
Alias
4-(4,4,5,5-tetramethyl-1,3,2-dioxborane-2-yl)-1H-pyrrolo[2,3-B]pyridine
CAS Number
942919-26-8
blur_circular Chemical Specifications
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Molecular Information
Weight
244.10 g/mol
Formula
C₁₃H₁₇BN₂O₂
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Registry Numbers
MDL Number
MFCD11616360
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Physical Properties
Melting Point
250-254 °C
Boiling Point
405.7 °C at 760 mmHg
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Storage & Handling
Density
1.15 g/cm3
Storage
2-8°C, dry
description Product Description
Used primarily in Suzuki-Miyaura cross-coupling reactions, this compound serves as a key boronic ester reagent in the synthesis of biaryl and heterobiaryl structures. Its pyrrolopyridine core makes it valuable in pharmaceutical and agrochemical research, especially in the development of kinase inhibitors and other bioactive molecules. The boronate ester group allows for efficient and selective carbon-carbon bond formation under mild conditions, making it suitable for late-stage functionalization in drug discovery. It is also employed in materials science for constructing conjugated organic frameworks used in optoelectronic devices.
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