2-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)isoindoline-1,3-dione
95%
Reagent
Code: #242208
Alias
4-phthaliminomethylphenylborate
CAS Number
138500-87-5
blur_circular Chemical Specifications
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Molecular Information
Weight
363.22 g/mol
Formula
C₂₁H₂₂BNO₄
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Registry Numbers
MDL Number
MFCD02179489
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Physical Properties
Boiling Point
504°C at 760 mmHg
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Storage & Handling
Storage
2-8°C
description Product Description
Widely used in organic synthesis, particularly in Suzuki-Miyaura cross-coupling reactions, this compound serves as a key boronic ester precursor. Its primary application lies in the construction of biaryl and aryl-heteroaryl frameworks, which are common structural motifs in pharmaceuticals, agrochemicals, and functional materials. The presence of the isoindoline-1,3-dione group enhances stability and can act as a protecting group or directing handle in multi-step syntheses. It is especially valuable in drug discovery and development for enabling efficient carbon-carbon bond formation under mild conditions.
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