tert-butyl (3-((4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)methylene)cyclobutyl)carbamate
99%
Reagent
Code: #242148
blur_circular Chemical Specifications
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Molecular Information
Weight
309.21 g/mol
Formula
C₁₆H₂₈BNO₄
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Storage & Handling
Storage
2-8℃
description Product Description
Used primarily as an intermediate in Suzuki-Miyaura cross-coupling reactions, this compound enables the formation of carbon-carbon bonds in complex organic syntheses. Its boronate ester group reacts efficiently with aryl or vinyl halides in the presence of a palladium catalyst, making it valuable in pharmaceutical and agrochemical research for constructing substituted cyclobutane derivatives. The tert-butyl carbamate (Boc) protecting group stabilizes the amine during reactions and can be easily removed under mild acidic conditions when needed. This combination of reactivity and protection makes it useful in multi-step synthesis of bioactive molecules.
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