Tert-butyl 3-(5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiophen-3-yl)pyrrolidine-1-carboxylate
95%
Reagent
Code: #242060
CAS Number
2223003-52-7
blur_circular Chemical Specifications
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Molecular Information
Weight
379.3218 g/mol
Formula
C₁₉H₃₀BNO₄S
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Storage & Handling
Storage
-20°C, sealed, dry
description Product Description
Used in organic synthesis as a key intermediate in Suzuki-Miyaura cross-coupling reactions, enabling the formation of carbon-carbon bonds for constructing complex molecules. Its boronic ester group readily reacts with aryl or heteroaryl halides under palladium catalysis, making it valuable in pharmaceutical and agrochemical research for building substituted thiophene and pyrrolidine derivatives. The tert-butyl carbamate (Boc) protecting group ensures stability and controlled deprotection of the pyrrolidine nitrogen during multi-step syntheses. Commonly employed in the development of bioactive compounds and functional materials requiring precise molecular architecture.
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