Tert-butyl 3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazol-2-yl)pyrrolidine-1-carboxylate
95%
Reagent
Code: #242054
CAS Number
2222995-74-4
blur_circular Chemical Specifications
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Molecular Information
Weight
380.30986 g/mol
Formula
C₁₈H₂₉BN₂O₄S
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Storage & Handling
Storage
-20°C, sealed, dry
description Product Description
Used in organic synthesis as a key intermediate for Suzuki-Miyaura cross-coupling reactions, enabling the formation of carbon-carbon bonds in pharmaceutical and agrochemical development. The boronate ester group facilitates coupling with aryl or heteroaryl halides under palladium catalysis, making it valuable for constructing complex heterocyclic systems. Commonly employed in medicinal chemistry for the synthesis of bioactive molecules, particularly those containing thiazole and pyrrolidine motifs. Its protected amine group allows for further functionalization after coupling, offering versatility in multi-step synthetic routes.
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