1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)-3-(3-(trifluoromethyl)phenyl)urea
95%
Reagent
Code: #242041
CAS Number
796967-48-1
blur_circular Chemical Specifications
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Molecular Information
Weight
406.206 g/mol
Formula
C₂₀H₂₂BF₃N₂O₃
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Storage & Handling
Storage
2-8°C
description Product Description
Used as a key intermediate in Suzuki-Miyaura cross-coupling reactions for the synthesis of biaryl compounds in pharmaceutical and agrochemical research. Its boronate ester group enables efficient carbon-carbon bond formation under mild conditions. The trifluoromethylphenyl urea moiety contributes to enhanced metabolic stability and binding affinity in bioactive molecule development. Commonly employed in the preparation of kinase inhibitors and other therapeutic agents where fluorinated aromatic structures improve pharmacokinetic properties. Also applied in materials science for constructing conjugated organic frameworks with tunable electronic characteristics.
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