[4-(tert-butylcarbamoyl)-3-chloro-phenyl]boronic acid
97%
Reagent
Code: #242013
CAS Number
850589-46-7
blur_circular Chemical Specifications
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Molecular Information
Weight
255.5057 g/mol
Formula
C₁₁H₁₅BClNO₃
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Registry Numbers
MDL Number
MFCD07363771
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Physical Properties
Melting Point
130-134 °C
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Storage & Handling
Density
1.24 g/cm3
Storage
2-8°C, dry
description Product Description
Used in Suzuki-Miyaura cross-coupling reactions for the synthesis of biaryl compounds in pharmaceutical and agrochemical research. Its boronic acid group enables efficient carbon-carbon bond formation under mild conditions. The presence of a tert-butylcarbamoyl group enhances stability and influences electronic properties, improving selectivity in coupling reactions. Commonly employed in the development of active pharmaceutical ingredients (APIs) where chloro-substituted aromatic systems are required as intermediates. Also utilized in materials science for constructing conjugated organic frameworks with tailored electronic characteristics.
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