1-[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]ethanone
97%
Reagent
Code: #241546
CAS Number
214360-49-3
blur_circular Chemical Specifications
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Molecular Information
Weight
246.1099 g/mol
Formula
C₁₄H₁₉BO₃
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Registry Numbers
MDL Number
MFCD05863923
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Physical Properties
Boiling Point
362.5°C at 760 mmHg
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Storage & Handling
Storage
2-8℃
description Product Description
Used primarily in organic synthesis as a key intermediate in Suzuki-Miyaura cross-coupling reactions, enabling the formation of carbon-carbon bonds. Its boronate ester group readily reacts with aryl or vinyl halides in the presence of a palladium catalyst, making it valuable for constructing biaryl compounds commonly found in pharmaceuticals, agrochemicals, and advanced materials. The ketone functional group allows for further derivatization, such as reduction to alcohols or conversion to imines, enhancing its utility in multi-step synthesis. Commonly employed in the development of active pharmaceutical ingredients (APIs) and conjugated systems for optoelectronic materials.
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