Used primarily in organic synthesis as a versatile building block for Sonogashira and Suzuki-Miyaura cross-coupling reactions. The presence of both alkyne and boronate ester functional groups allows for sequential or selective transformations, enabling the construction of complex conjugated systems. Commonly employed in the development of organic electronic materials, such as semiconducting polymers and small-molecule conjugates for OLEDs and organic photovoltaics. Its trimethylsilyl-protected alkyne offers improved stability and handling, with the protecting group easily removed under mild conditions to liberate the terminal alkyne for further derivatization. Also utilized in click chemistry and bioconjugation strategies where controlled, stepwise coupling is required.