4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)isoxazole
98%
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Widely used in Suzuki-Miyaura cross-coupling reactions, this compound serves as a key building block for forming carbon-carbon bonds in pharmaceutical and agrochemical synthesis. Its isoxazole ring is a common heterocycle in bioactive molecules, making this reagent valuable for constructing drug-like scaffolds. It enables efficient introduction of the isoxazole moiety into larger aromatic systems under palladium catalysis, which is critical in the development of active pharmaceutical ingredients (APIs). Due to the stability and reactivity of the boronate ester group, it is preferred in high-yielding, selective couplings under mild conditions. It is also employed in the synthesis of functional materials, including organic semiconductors and fluorescent probes.
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