4,4,5,5-Tetramethyl-2-(3-(trifluoromethyl)phenyl)-1,3,2-dioxaborolane
95%
Reagent
Code: #240719
CAS Number
325142-82-3
blur_circular Chemical Specifications
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Molecular Information
Weight
272.07 g/mol
Formula
C₁₃H₁₆BF₃O₂
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Registry Numbers
MDL Number
MFCD05863925
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Physical Properties
Melting Point
43°C
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Storage & Handling
Storage
2-8°C
description Product Description
Used as a key reagent in Suzuki-Miyaura cross-coupling reactions, enabling the formation of carbon-carbon bonds in pharmaceutical and agrochemical synthesis. Its arylboron structure provides high stability and reactivity with palladium catalysts, making it valuable for constructing complex organic molecules, especially in drug development. The electron-withdrawing trifluoromethyl group enhances the electrophilicity of the aromatic ring, improving coupling efficiency. Commonly employed in late-stage functionalization due to its tolerance of various functional groups and mild reaction conditions.
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