2-(Pyrrolidin-1-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)nicotinonitrile
96%
science Other reagents with same CAS 1356068-52-4
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Used as a key intermediate in Suzuki-Miyaura cross-coupling reactions for the synthesis of biologically active compounds, particularly in pharmaceutical and agrochemical research. Its boronate ester group enables efficient carbon-carbon bond formation with aryl or heteroaryl halides, facilitating the construction of complex nitrogen-containing heterocyclic systems. The nitrile and pyrrolidine functionalities enhance binding selectivity in medicinal chemistry applications, making it valuable in the development of kinase inhibitors and CNS-targeted drugs. Also employed in materials science for designing electron-transport layers in organic electronics due to its stable conjugated structure.
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