N-(4-Chloro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetamide
98%
Reagent
Code: #219647
CAS Number
1218789-92-4
blur_circular Chemical Specifications
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Molecular Information
Weight
295.57 g/mol
Formula
C₁₄H₁₉BClNO₃
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Registry Numbers
MDL Number
MFCD15143594
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Physical Properties
Boiling Point
454.6±40.0 °C at 760 mmHg
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Storage & Handling
Density
1.16±0.1 g/cm3(Predicted)
Storage
Room temperature, dry
description Product Description
Used as an intermediate in Suzuki-Miyaura cross-coupling reactions, this compound enables the formation of carbon-carbon bonds in the synthesis of complex organic molecules. Its boronate ester group reacts with aryl or vinyl halides in the presence of a palladium catalyst, making it valuable in pharmaceutical and agrochemical research for constructing biaryl scaffolds. The acetamide functionality can act as a directing or protecting group during transformations, enhancing selectivity. It is particularly useful in medicinal chemistry for building substituted aromatic systems found in bioactive compounds.
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