3-Nitro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
97%
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Used primarily in cross-coupling reactions, this compound serves as a key building block in the synthesis of pharmaceuticals and agrochemicals. Its boronate ester group enables Suzuki-Miyaura coupling, allowing efficient formation of carbon-carbon bonds with aryl or heteroaryl halides. This makes it valuable in medicinal chemistry for constructing complex nitrogen-containing heterocycles. It is also employed in materials science for developing organic electronic materials, where precise molecular architecture is critical. The presence of the nitro group offers a handle for further functionalization, such as reduction to an amine, enabling diverse derivatization pathways in compound libraries for drug discovery.
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