N-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)formamide
≥95%
Reagent
Code: #215721
CAS Number
480424-94-0
blur_circular Chemical Specifications
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Molecular Information
Weight
247.1 g/mol
Formula
C₁₃H₁₈BNO₃
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Registry Numbers
MDL Number
MFCD03789266
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Physical Properties
Melting Point
116.7-118.2 °C
Boiling Point
403.6±28.0 °C(Predicted)
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Storage & Handling
Density
1.09±0.1 g/cm3(Predicted)
Storage
2-8°C, Sealed, Inert Gas
description Product Description
Used primarily as an intermediate in Suzuki-Miyaura cross-coupling reactions, enabling the formation of carbon-carbon bonds in the synthesis of complex organic molecules. Its boronate ester group reacts efficiently with aryl halides under palladium catalysis, making it valuable in pharmaceutical and agrochemical research for constructing biaryl frameworks. The presence of the formamide group allows for further functionalization or serves as a directing group in subsequent transformations. Commonly employed in medicinal chemistry for library synthesis and drug discovery due to its stability and reactivity profile.
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