2-Methyl-2-[3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-propionitrile
98%
Reagent
Code: #213440
CAS Number
1160502-10-2
blur_circular Chemical Specifications
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Molecular Information
Weight
271.17 g/mol
Formula
C₁₆H₂₂BNO₂
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Registry Numbers
MDL Number
MFCD19689511
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Storage & Handling
Storage
Room temperature, seal, dry
description Product Description
Used primarily as a key intermediate in Suzuki-Miyaura cross-coupling reactions, this compound enables the formation of carbon-carbon bonds in the synthesis of complex organic molecules. Its boronate ester group readily participates in palladium-catalyzed couplings with aryl or vinyl halides, making it valuable in pharmaceutical and agrochemical research. The nitrile and sterically hindered tertiary carbon center allow for further functionalization, supporting the construction of structurally diverse and biologically active compounds. It is especially useful in medicinal chemistry for building aromatic frameworks found in drug candidates.
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