2-Methoxy-3-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
98%
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Used primarily as a key intermediate in Suzuki-Miyaura cross-coupling reactions, this compound enables the formation of carbon-carbon bonds in the synthesis of complex organic molecules. Its boronate ester group readily reacts with aryl or heteroaryl halides in the presence of a palladium catalyst, making it valuable in pharmaceutical and agrochemical research. It is especially useful for constructing substituted pyridine derivatives, which are common scaffolds in drug discovery. The methoxy and methyl substituents help modulate electronic and steric properties, enhancing selectivity and yield in coupling reactions. Its stability and reactivity profile make it suitable for use in automated synthesis and library generation for high-throughput screening. Additionally, this compound is utilized in the synthesis of organic materials for electronic devices, such as OLEDs and organic transistors, allowing for the fine-tuning of electrical properties through coupling with other aromatic systems.
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