4-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Thiazole
97%
Reagent
Code: #212761
CAS Number
1662682-33-8
blur_circular Chemical Specifications
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Molecular Information
Weight
225.12 g/mol
Formula
C₁₀H₁₆BNO₂S
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Storage & Handling
Storage
Room temperature
description Product Description
Used in Suzuki-Miyaura cross-coupling reactions as a key boronic ester reagent for constructing biaryl and heteroaryl frameworks in pharmaceutical and agrochemical synthesis. Its thiazole core enables the development of bioactive molecules, particularly in drug discovery where nitrogen-sulfur heterocycles are prevalent. The boronate ester group provides high stability and reactivity under mild palladium-catalyzed conditions, making it valuable for late-stage functionalization in complex molecule assembly. Also applied in materials science for synthesizing conjugated organic semiconductors and fluorescent probes due to its electron-accepting properties and structural rigidity.
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