Methyl 4-(4, 4, 5, 5-tetramethyl-1, 3, 2-dioxaborolan-2-yl)-3-(trifluoromethyl)benzoate
96%
Reagent
Code: #211464
CAS Number
1371589-09-1
blur_circular Chemical Specifications
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Molecular Information
Weight
330.11 g/mol
Formula
C₁₅H₁₈BF₃O₄
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Registry Numbers
MDL Number
MFCD23379538
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Physical Properties
Boiling Point
375.6±42.0 °C(Predicted)
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Storage & Handling
Density
1.21±0.1 g/cm3(Predicted)
Storage
2-8°C, dry
description Product Description
Widely used in Suzuki-Miyaura cross-coupling reactions, this compound serves as a key building block in the synthesis of complex organic molecules, especially in pharmaceutical and agrochemical industries. The presence of the trifluoromethyl group enhances metabolic stability and lipophilicity in drug candidates, making this reagent valuable for constructing bioactive molecules. Its boronate ester functionality allows for efficient and selective carbon-carbon bond formation under mild conditions. It is particularly useful in the preparation of fluorinated aromatic compounds, which are common motifs in modern medicinal chemistry. Additionally, it supports late-stage functionalization strategies in drug development due to its compatibility with various functional groups and catalytic systems.
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