1-(Methylsulfonyl)-4-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)piperidine
≥95%
science Other reagents with same CAS 1428329-80-9
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description Product Description
Used in organic synthesis as a key intermediate in Suzuki-Miyaura cross-coupling reactions, enabling the formation of carbon-carbon bonds for constructing biaryl and heterobiaryl systems. Its boronate ester group readily reacts with aryl or heteroaryl halides in the presence of palladium catalysts, making it valuable in pharmaceutical and agrochemical research for developing complex aromatic structures. The methylsulfonyl group enhances solubility and can act as a directing or stabilizing moiety in target molecules. Commonly employed in medicinal chemistry for lead optimization and library synthesis.
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