4-Methylbenzeneboronic acid neopentyl glycol ester
98%
science Other reagents with same CAS 380481-66-3
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Used as a key reagent in Suzuki-Miyaura cross-coupling reactions, enabling the formation of carbon-carbon bonds in pharmaceutical and agrochemical synthesis. Its ester form enhances stability and handling compared to the free boronic acid, making it suitable for large-scale industrial processes. Commonly employed in the preparation of biaryl compounds, which are structural motifs in many drug candidates and functional materials. The neopentyl glycol ester group improves crystallinity and reduces protodeboronation, leading to higher reaction yields and purity. Also utilized in combinatorial chemistry and medicinal chemistry for rapid library synthesis.
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