1-benzyl-3,3-difluoro-5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)indolin-2-one
98%
Reagent
Code: #207556
CAS Number
1704069-51-1
blur_circular Chemical Specifications
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Molecular Information
Weight
385.21 g/mol
Formula
C₂₁H₂₂BF₂NO₃
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Registry Numbers
MDL Number
MFCD28384366
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Storage & Handling
Storage
Room temperature, dry
description Product Description
Used in organic synthesis as a key intermediate for Suzuki-Miyaura cross-coupling reactions, enabling the formation of biaryl and aryl-heteroaryl bonds in pharmaceutical development. Its boronate ester group facilitates efficient coupling with aryl halides under palladium catalysis, making it valuable in constructing complex molecules for drug discovery. Particularly useful in synthesizing kinase inhibitors and other bioactive compounds where fluorinated indolinone scaffolds enhance metabolic stability and binding affinity.
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