Methyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(trifluoromethyl)benzoate
95%
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Widely used in Suzuki-Miyaura cross-coupling reactions, this compound serves as a key building block in the synthesis of complex organic molecules, particularly in pharmaceutical and agrochemical industries. Its boronate ester group enables efficient carbon-carbon bond formation under mild conditions, making it valuable for constructing biaryl and heterobiaryl systems. The presence of the trifluoromethyl group enhances the metabolic stability and lipophilicity of target molecules, which is advantageous in drug design. Additionally, the ester functionality allows for further derivatization, such as hydrolysis or reduction, enabling versatile downstream modifications. It is especially useful in the development of fluorinated active pharmaceutical ingredients (APIs) where controlled structure and electronic properties are critical.
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