1-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-5-carbonitrile
≥97%
Reagent
Code: #203019
CAS Number
2197909-49-0
blur_circular Chemical Specifications
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Molecular Information
Weight
233.07 g/mol
Formula
C₁₁H₁₆BN₃O₂
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Registry Numbers
MDL Number
MFCD31746131
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Physical Properties
Boiling Point
385.7±27.0 °C(Predicted)
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Storage & Handling
Density
1.11±0.1 g/cm3(Predicted)
Storage
2-8°C, Inert Gas
description Product Description
Used as a key intermediate in Suzuki-Miyaura cross-coupling reactions for the synthesis of biologically active compounds, particularly in pharmaceutical and agrochemical research. Its boronate ester group enables efficient carbon-carbon bond formation with aryl or heteroaryl halides under palladium catalysis. The nitrile and methyl-substituted pyrazole moieties enhance binding selectivity in drug design, making this compound valuable in developing kinase inhibitors and other targeted therapies. It is also employed in the preparation of functional materials such as organic semiconductors due to its stable heterocyclic framework and electronic properties.
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