4,4,5,5-tetramethyl-2-(4-(tetrahydro-2H-pyran-2-yl)thiophen-2-yl)-1,3,2-dioxaborolane
95%
Reagent
Code: #195842
CAS Number
2223005-72-7
blur_circular Chemical Specifications
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Molecular Information
Weight
294.21732 g/mol
Formula
C₁₅H₂₃BO₃S
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Storage & Handling
Storage
-20°C, sealed, dry
description Product Description
Used as a key intermediate in Suzuki-Miyaura cross-coupling reactions, enabling the formation of carbon-carbon bonds in pharmaceutical and agrochemical synthesis. Its boronate ester group facilitates coupling with aryl or heteroaryl halides under palladium catalysis, making it valuable in constructing complex organic molecules. The tetrahydropyranyl (THP) protecting group enhances stability and solubility during multi-step syntheses, particularly in the development of conjugated materials and bioactive compounds. Commonly employed in research settings for preparing functionalized thiophene derivatives used in organic electronics and medicinal chemistry.
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