1-(4-Fluorophenyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole
98%
Reagent
Code: #192711
CAS Number
1373918-57-0
blur_circular Chemical Specifications
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Molecular Information
Weight
288.13 g/mol
Formula
C₁₅H₁₈BFN₂O₂
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Registry Numbers
MDL Number
MFCD16987650
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Physical Properties
Boiling Point
386.3±22.0 °C(Predicted)
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Storage & Handling
Density
1.14±0.1 g/cm3(Predicted)
Storage
2-8°C, Sealed, Inert Gas
description Product Description
Used as a key intermediate in Suzuki-Miyaura cross-coupling reactions for the synthesis of biologically active compounds, particularly in pharmaceutical and agrochemical research. Its boronate ester group enables efficient carbon-carbon bond formation with aryl or heteroaryl halides, facilitating the construction of complex pyrazole derivatives. Commonly employed in the development of fluorinated drug candidates due to enhanced metabolic stability and membrane permeability imparted by the fluorophenyl moiety. Also utilized in materials science for creating novel organic semiconductors and fluorescent probes.
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