tert-Butyl (5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2,3-dihydro-1H-inden-2-yl)carbamate
98%
Reagent
Code: #192529
CAS Number
1338547-17-3
blur_circular Chemical Specifications
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Molecular Information
Weight
359.27 g/mol
Formula
C₂₀H₃₀BNO₄
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Registry Numbers
MDL Number
MFCD16987837
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Physical Properties
Boiling Point
477.4±45.0 °C(Predicted)
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Storage & Handling
Density
1.09±0.1 g/cm3(Predicted)
Storage
2-8°C, Sealed, Inert Gas
description Product Description
Used primarily in organic synthesis as a protected boronic ester intermediate for Suzuki-Miyaura cross-coupling reactions. The tert-butyl carbamate (Boc) group stabilizes the amine functionality during coupling, allowing selective reaction at the boron site. After coupling, the Boc group can be easily removed under mild acidic conditions to liberate the free amine, enabling further functionalization. Commonly employed in the synthesis of pharmaceuticals and bioactive molecules where indane or indoline scaffolds are required. Its stability and compatibility with a wide range of reaction conditions make it valuable in multi-step synthetic routes, especially in drug discovery and development.
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